Argireline is an anti-wrinkle cosmetics ingredient and a peptide.  It is sold by Lipotec, which is a company based in the Barcelona area.  This patented formula is gaining a lot of attention as of late because of its claims to halt wrinkles.  It’s been called Botox without the hassle.  How does this miracle working substance compare to Matrixyl, another commonly known product?

If you have been researching Argireline for quite a while, you may have already run across a substance known as Matrixyl.  Both Argireline and Matrixyl are peptides, and these are the building blocks of living tissue.  Peptides, which are basically small fragments of proteins that have their own ways of affecting cells and interacting with them, are often used in special skin formulations.  These products are used to prevent wrinkles and typically come in the form of a cream.  Argireline and Matrixyl, when combined with other ingredients such as supplements and vitamins, are marketed as helping to reduce the effects of age on the skin.  These two peptides, however, have entirely different properties and purposes.


By now in your research, you have seen that Argireline works in similar fashion to Botox, but without the injections and resultant pain.  Both Argireline and Botox block the release of neurotransmitters to the muscles of the face from neurons.  In order to contraction of muscles to take place, these neurotransmissions are necessary.  However, while Botox works deep within facial tissue, and can only be applied through a needle, Argireline relaxes muscles near the top of the skin.  As a result, this topical cream eliminates wrinkles.  According to a 2002 study performed by the Molecular and Cellular Biology Center in Alicante, Spain, volunteers using a cream containing Argireline for 30 days continuously saw their wrinkles reduced by 30 percent.


In contrast, Matrixyl works in a very different manner.  While Argireline (in a similar manner to Botox) paralyzes the muscles of the face so that wrinkles are reduced, Matrixyl helps to grow collagen and other proteins, including glucosaminoglycans and elastin.  All of these compounds provide important support for the skin.  When collagen breaks down, that is a main cause of wrinkles and folds.

A study was recently performed in Germany studying the effects of a cream containing Matrixyl on skin problems experienced by women suffering from breast cancer who had undergone radiation treatment.  The study showed Matrixyl was a possible agent for combating skin problems, although it did not find Matrixyl to be any more effective than other therapies that are commonly used.